Find exactly what you're looking for with our easy to navigate hotel reservations planner, and make your plans in seconds.. Locate Clarksdale hotels right near where you plan to work or play, and find discounts on activities, such as car rentals and even golf. Find bargains on entertainment, clothing, and things to do while walking around main street. Navigate the tabs at the top of our pages to find information on hotels in Clarksdale and all the amenities they have to offer, plus all you need to know about visiting this wonderful city. Remember to include in your stay some outdoor relaxing activities like fishing, golfing, boating and site seeing.